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The Conversation
The Conversation
Eleftheria Kodosaki, Research Fellow in Neuroimmunology, UCL

Size of brain area linked with cognitive decline – even in people with no other warning signs of Alzheimer’s disease

Previous research has shown loss of volume in the hippocampus precedes signs of cognitive decline in people with Alzheimer's. Atthapon Raksthaput/ Shutterstock

A small, seahorse-sized area of the brain is responsible for most of our learning and memory. Called the hippocampus, this area is key to many important brain functions, including turning short-term memories into long-term ones, regulating our emotions and making spatial navigation possible – essentially, our ability to plan where to go and how to get there.

As we get older, it’s normal for the hippocampus to shrink somewhat. But with certain health conditions, this volume loss is more rapid. Unsurprisingly, Alzheimer’s disease is one of these conditions.

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