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Tracy Hussell, Director of the Lydia Becker Institute of Immunology and Inflammation, University of Manchester

Shortages, substitutes and uncertainty: the new reality of drugs supplies

Yaroslav Astakhov/Shutterstock.com

The reliable supply of drugs is fundamental to any healthcare system, yet shortages remain a persistent problem.

Disruptions arise from a range of causes: manufacturing failures, fluctuating demand, regulatory changes and wars. Around 60% of drug shortages are linked to manufacturing bottlenecks, while insufficient reserves of both finished products and raw ingredients continue to leave health systems like the NHS exposed.

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