Scientists studying the strange biology of Naked mole rat have identified genetic mechanisms that may one day help humans heal better, resist aging, and possibly regenerate damaged tissues. The breakthrough focuses on a special gene linked to unusually high levels of high molecular weight hyaluronic acid (HMW-HA), a substance strongly associated with the naked mole rat’s extraordinary resistance to disease and aging.
Researchers at the University of Rochester transferred this gene into mice and recorded significant health improvements that included better protection against cancer, minimized inflammation, and a modest increase in lifespan. Their findings were published in the scientific journal Nature in 2023.
