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The Guardian - UK
The Guardian - UK
Science
Ian Sample Science editor

Scientists hail autoimmune disease therapy breakthrough

A lab technician
CAR T-cell therapy has been most widely used in the treatment of blood cancers so far. Photograph: Thomas Coex/AFP/Getty Images

Five people with severe autoimmune disease have become the first in the world to receive a groundbreaking therapy that uses genetically altered cells to drive the illness into remission.

The four women and one man, aged 18 to 24, received transfusions of modified immune cells to treat severe lupus, an autoimmune disease that can cause life-threatening damage to the heart, lungs, brain and kidneys.

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