A new international review offers early, cautious reassurance for women who discover they are pregnant while taking a GLP-1 medicine such as Ozempic or Mounjaro. After pooling seven studies that included more than 43,000 women exposed to these drugs, researchers found no significant link between exposure, mostly in the first trimester, and preterm birth, stillbirth, newborn death, preeclampsia, or babies born small for their gestational age.
The analysis was published Sept. 29 in The Lancet Obstetrics, Gynaecology & Women's Health and presented at the European Association for the Study of Diabetes meeting in Milan. It does not show that the drugs are safe in pregnancy, and it does not change advice to stop them before a planned pregnancy. Women who learn they are pregnant while on one of these medicines should call the clinician who prescribes it right away.