In a matchup between two franchises in similar spots, something’s got to give.
San Francisco (6-8) enters after dropping a Week 15 Thursday night game versus the Los Angeles Rams that effectively ended the 49ers’ final playoff hopes.
Meanwhile, Miami (6-8) is on the outside looking in on the AFC playoffs picture as well.
With both teams also navigating notable injury reports, which club shows up and wants this game more?
As kickoff approaches, here’s a look at the latest odds, including the point spread, money line figures and the over-under total. Plus, a prediction and a best bet for how the matchup unfolds.
49ers vs. Dolphins game odds:
All NFL Odds via BetMGM:
- Point spread: 49ers -1.5
- Money line: 49ers -125 / Dolphins +105
- Over-under: 44.5
49ers vs. Dolphins injury updates:
- 49ers RB Isaac Guerendo – OUT (foot, hamstring)
- 49ers OT Trent Williams – OUT (ankle)
- 49ers DL Nick Bosa – Questionable (hip, oblique)
- 49ers LB Dre Greenlaw – Questionable (Achilles, knee)
- 49ers DL Robert Beal Jr. – Questionable (ankle)
- Dolphins OT Terron Armstead – Questionable (knee)
- Dolphins OT Kendall Lamm – Questionable (back)
- Dolphins WR Tyreek Hill – Questionable (wrist, rest)
- Dolphins WR Jaylen Waddle – Doubtful (knee)
- Dolphins OLB Bradley Chubb – OUT knee)
- Dolphins LS Blake Ferguson – OUT (non-football illness)
49ers vs. Dolphins prediction, pick
Prediction: 49ers 24, Dolphins 20
In what is truly a coin-flip game, San Francisco shows some pride on the road to down the Dolphins. Given the 49ers’ depleted running back situation, think about San Francisco running back Patrick Taylor as an anytime touchdown scorer at +110 odds.
49ers vs. Dolphins channel, start time, streaming:
The 49ers vs. Dolphins game starts at 1:25 p.m. PT and can be seen on CBS.
Get more betting analysis and predictions at Sportsbook Wire.
