There is 'no forensic evidence' to support allegations of spiking by injection, Police Scotland has said.
There was a record number of reports of spiking made to the force last year including 51 people believed to have been injected.
Several victims came forward on social media to recount their experiences of falling seriously ill and discovering puncture marks and bruising on their backs, arms, and legs.
However, a senior detective in Police Scotland said that no substances linked to drink spiking were discovered during investigations.
Detective Chief Superintendent Laura McLuckie told the Scottish Police Authority: “I’m pleased to say that we’re not seeing any drugs within people’s systems that we would class as being a drug that would be used in spiking.
“There is clearly alcohol involved. There is clearly recreational drug use involved.
“However, we don’t have any identified cases of any spiking by injection in Scotland at this time.
"We will obviously continue to monitor over the coming weeks and months."
Reports of spiking by injection are now on a "significant downward trajectory" with no reports filed in Scotland in the last week. 10 cases were recorded on December 20 which then dropped to three cases in the weeks afterward.
In the first 10 months of 2021, police investigated 152 cases of drugs being added to drinks or injections with syringes.
69 people reported they'd had their drink spiked, with 51 people being injected. Of the remaining 32 cases police were unable to establish how they had been drugged.
It is often the case that substances are out of the sytem within 24 hours.
Assistant Chief Constable Gary Ritchie, Police Scotland, said: "We continue to investigate reports from people having been “spiked” either with a needle or in their drink. We are not always able to determine the reasons why a perpetrator carries out an assault in this way. Every report is and will be taken seriously and fully investigated and that will include a full forensic investigation when appropriate.
“People, should be able to go out for a night out without fear of being spiked. We are working with a range of partners, both locally and nationally, to ensure licensed premises are safe spaces for all, through the continued delivery of ByStander Awareness training.
“We are also working in partnership with other emergency services, student bodies, universities/colleges, and third sector organisations to raise awareness and provide support for anyone affected.
“We would encourage anyone who believes they have had their drink spiked or been assaulted in this way to contact Police Scotland on 101 or in an emergency 999."