
Path of Exile 2 basically exists as two different games: the campaign, and the Atlas of Worlds. Once you get to the Atlas, you'll start progressing through 15 tiers of waystones until you get to the very toughest monsters. Along the way you'll start to encounter all sorts of new mechanics and challenges, most of which will add some sort of horrible danger in exchange for goodies.
Some of these mechanics have their own skill trees, and by engaging with them and defeating their pinnacle bosses, you can earn points to make them even more challenging and rewarding. Here I'll break down all the major endgame systems of Path of Exile 2, give you some tips on how to get those points faster, and provide some basic sense of how to make currency with each one.