Over four decades, the Children's Cancer Run and the generosity of the North East community has supercharged cancer research and seen the region "really play its part" in dramatically improving the odds for youngsters with the horrendous disease.
Speaking ahead of the 40th anniversary edition of the run - taking place at Newcastle Racecourse on Sunday May 14, Professor Sir Alan Craft and Colin Peacock reflected on the vital role the run has played fundraising to support doctors treating unwell children in our region.
Both men were present at the creation of the run - Sir Alan founded Newcastle's children's cancer unit and Colin's son Chris survived chidlhood cancer - and they paid tribute to the thousands of people who've taken part, the volunteers who came back year after year, and the fact that people in the North East have always been willing to put their hands in their pockets for a good cause.