Scientists have created a pill that mimics the positive health benefits of a workout.
Researchers at Aarhus University in Denmark said the molecule, named LaKe, could have the same health impact as running a 10k at a high speed.
The pill contains a molecule that can mimic the body’s natural metabolic response to exercise and fasting.
Exercise helps to increase levels of lactates and ketones in the body, which act as efficient fuel for cells.
This increases the production of an appetite-suppressing hormone increases, while decreasing the level of free fatty acids in the blood.
Dr Thomas Poulsen, a chemist at Aarhus University who led the research, said: “It can be difficult to maintain motivation to run many kilometers at high speed and go without food.
“For people with physical ailments, such as a weak heart or general weakness, a nutritional supplement can be the key to better recovery.”
LaKe has shown positive results in a study of rats and the first human clinical trials are underway in at Aarhus University Hospital.
If successful, it could be developed into a nutritional supplement.
Scientists hope the drug will help people who cannot follow a strict exercise and diet plan but cautioned that it may take years to produce.
Dr Poulsen added: “It can be difficult to maintain motivation to run many kilometres at high speed and go without food. For people with physical ailments such as a weak heart or general weakness, a nutritional supplement can be the key to better recovery.”
The molecule also has potential to alleviate concentration difficulties and may be used in the treatment of serious diseases such as Parkinson's and dementia, researchers said.
These diseases are often characterised by low energy levels in the brain, which inhibit its optimal functioning
“Because lactate can take over the role of glucose in the brain under stressful or traumatic conditions, there have been experiments to increase lactate levels in people with concussion. Patients who cannot perform strenuous exercise will benefit greatly from a drug that can boost these,” Dr Poulsen said.
The study was published in the Journal or Agricultural and Food Chemistry.
