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Colin Davidson, Professor of Neuropharmacology and Head of School of Pharmacy & Biomedical Sciences, University of Central Lancashire

Nitazenes: synthetic opioids more deadly than fentanyl are starting to turn up in overdose cases

The synthetic opioid fentanyl is well known for the many lives it has claimed – mainly in the US, but elsewhere too. Now, a less well-known class of synthetic opioids called nitazenes is starting to crop up in overdose cases, on both sides of the Atlantic.

Nitazenes have recently been the subject of a national patient safety alert in the UK as a result of a spike in opioid-related deaths over the last two months, with several cases involving nitazenes.

Some drugs in the nitazene class are 100 times more potent than morphine – so about as potent as fentanyl. However, nitazenes may be more deadly.

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