First Minister Nicola Sturgeon has announced the end of the requirement for secondary school pupils to wear face masks in the classroom.
The change will come into effect when pupils return after the school half-term break on February 28.
Speaking in Holyrood on Thursday, Ms Sturgeon said the new rules will include school assemblies and visits from primary children preparing to go to secondary school.
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But she also confirmed pupils will still be required to don coverings in indoor communal areas of schools.
Ms Sturgeon said: "They represent a further step in allowing children and young people return to a more normal experience of school after many, many months of sacrifice and I hope they will be welcomed."
The news comes after the FM sounded a positive note at her coronavirus briefing on Tuesday.
She said: "The situation now remains much more positive than it was at the turn of the year - and thanks to a combination of vaccinations, targeted protective measures and the responsible reaction of the public, it is much more positive than we feared it might be at this stage.
"It seems reasonable, based on the data, to conclude that we are now through the worst of this wave of Omicron.
"That has enabled the removal of virtually all the additional measures that we introduced in December and a return to normality in much of everyday life."
Sturgeon added: "We are on a good track at this stage. To stay on this track, though, continued care and caution remains necessary.
"While much more stable than it was, the virus is still widespread; (coronavirus rate of) one in 30 remains a high level of infection."