A new coronavirus variant, called XE, has been identified in the UK. The latest research from the UK Health Security Agency (UKHSA) reveals that XE is a mutation of the BA.1 and BA.2 Omicron strains, referred to as a 'recombinant'.
As of 22 March, there have been a confirmed 637 cases of XE in the UK, with the earliest recorded on 19 January 2022. According to the most recent data, as of 16 March 2022, the variant had a growth rate 9.8 per cent above that of the stealth variant, the UKHSCA said.
But the body cautioned that 'as this estimate has not remained consistent as new data have been added, it cannot yet be interpreted as an estimate of growth advantage for the recombinant.' "Numbers were too small for the XE recombinant to be analysed by region," the UKHSCA said.
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A recombinant variant occurs when an individual becomes infected with two or more variants at the same time, resulting in a mixing of their genetic material within the patient’s body, the UKHSA said. It added that it is not an 'unusual occurrence' and 'as with any other coronavirus variant, the vast majority do not confer any advantage to the virus and die out relatively quickly.'
Professor Susan Hopkins, Chief Medical Advisor, UKHSA said that this 'particular recombinant, XE, has shown a variable growth rate and we cannot yet confirm whether it has a true growth advantage.' She added: "So far there is not enough evidence to draw conclusions about transmissibility, severity or vaccine effectiveness.
"UKHSA will continue to monitor the situation closely as a matter of routine, as we do all data relating to SARS-CoV-2 variants both in the UK and internationally."
The UKHSA report added: “XE shows evidence of community transmission within England, although it is currently less than one per cent of total sequenced cases.”
THE UKHSA is also examining another two variants, known as XF and XD., which are recombinants of Delta and Omicron BA.1. In the UK, 38 cases of XF have been identified, though none have been seen since mid February.
There is currently no evidence of community transmission within the UK. XD has not been identified in the UK to date, though 49 cases have been reported globally, with the majority found in France.
With no legal restrictions now in place in England and the requirements to self-isolate removed, recent weeks have seen record numbers of people catching Covid. The Office for National Statistics said one in every 13 people - or 4.9 million - had the virus in the week ending March 26, up from 4.3 million in the previous week.