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LiveScience
LiveScience
Jennifer Zieba

New CRISPR system pauses genes, rather than turning them off permanently

An illustration of DNA breaking apart into tiny pieces.

Scientists have unveiled a new version of the famous gene-editing tool CRISPR, one that can "pause" a given gene temporarily rather than permanently turning it off.

The CRISPR revolution started in 2012, when Jennifer Doudna and Emmanuelle Charpentier — now Nobel winners — published their discovery of a new gene-editing technique more accurate and efficient than anything tried before. CRISPR has since transformed genetic research and was recently approved for a first-of-its-kind gene therapy for people with blood disorders.

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