Emergency services were called to reports of a serious collision involving a motorbike. It's understood the rider suffered serious injuries in the incident in Wigan.
Police and paramedics were called to Spring Road in Orrell - just past the Heinz factory - at around 2.50pm on Wednesday afternoon. No other vehicles were reportedly involved.
Exact details have not been revealed, but Greater Manchester Police have said initial enquiries were continuing. The scene remains closed by police for accident investigation work and according to reports, the air ambulance attended the scene together with firefighters.