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The Guardian - UK
The Guardian - UK
Science
Hannah Devlin Science correspondent

Molecule in python blood could pave way for new obesity drugs, scientists say

A Burmese python lying on grass
A Burmese python. The molecule, called pTOS, is produced by the snake’s gut bacteria and is also known to be present at low levels in human urine. Photograph: Rhona Wise/AFP/Getty Images

Pythons follow the ultimate crash diet, swallowing an antelope in a single sitting and then going for months without eating. Now scientists have identified a molecule that appears to be crucial for this metabolic feat, and which they say could pave the way for a new class of obesity drugs.

When the python metabolite, which spikes in their blood after eating, was given to obese mice, they shunned food and rapidly lost weight. The scientists said the molecule could have a similar effect to drugs such as Wegovy.

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