Arsenal's loss in the North London Derby had all the hallmarks of certain previous defeats this season and Mikel Arteta must ensure history doesn't repeat itself following Tottenham's win over Burnley.
What will have caused concern for the Spaniard as well as Gunners supporters - aside from the final result on Thursday night - is the potential central defensive crisis that could have a major impact on the club's hopes of sealing Champions League qualification for next season.
Not only is Rob Holding suspended for Monday night's clash against Newcastle United, but Arteta is sweating on the fitness of his first-choice pairing of Benjamin White and Gabriel Magalhaes after opting against risking the former against Spurs when the latter needed to be substituted.