Obesity has been a known factor influencing vaccine effectiveness. However, are there additional variables that affect the response? A recent study indicates that metabolic health at the time of vaccination plays a significant role in the efficacy of flu shots.
According to the results of an experimental study published in Nature Microbiology, switching obese mice to a healthy diet before flu vaccination completely protected them from a lethal dose of flu. However, switching the diet after vaccination did not help.
