A medieval disease is making a comeback across England - and our map shows the infections diagnosed near you as areas of Greater Manchester have some of the highest rates outside of London.
Cases of syphilis, the ancient sexually transmitted disease, increased by 15 per cent to nearly 8,700 diagnoses last year - the largest annual number since 1948. The UK Health Security Agency (UKHSA) says cases of syphilis have fluctuated over the last 100 years, spiking after the two world wars, but then declining in the late 1940s and 1950s due to effective treatment with penicillin, and greater availability of condoms.
It re-emerged in the 1960s but then fell into decline in the 1980s, probably due to behavioural changes brought about by the emergence and awareness of the HIV virus and AIDS. But since the early 2000s syphilis - and gonorrhoea - have re-emerged as major public health concerns.
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A decade ago there were 3,000 cases of syphilis diagnosed in England, just over a third as many as last year, while the infection rate has trebled from 5.6 syphilis cases per 100,000 of the population in 2012 to 15.4 last year. Dr Hamish Mohammed, Consultant Epidemiologist at the UK Health Security Agency (UKHSA), said: “Increased testing is likely to have played a part in the rise in gonorrhoea and syphilis diagnoses, but the scale of the increase strongly suggests that there is more transmission of these STIs within the population.
"There is some evidence to suggest that this may be due to more people having condomless sex with new or casual partners.”
UKHSA data shows syphilis disproportionally affects gay, bisexual, and other men who have sex with men (GBM). Seven in 10 of cases diagnosed last year (69 per cent) were in GBM. Syphilis is far more common in London than anywhere else in England.
The infection rate in the capital is 44.9 infections per 100,000 of the population. Also, 16 of the 20 local authority areas with the highest rates of infection are in London. Syphilis is most common in Lambeth (143.3 infections per 100,000 of the population), followed by Southwark (133.2) and Westminster (128.2).
Outside London, the highest rates are in Brighton and Hove (53.9), Salford (45.4), Middlesbrough (44.5), and Manchester (42.9). You can see the number and rate of syphilis infections where you live using our interactive map.
Research published in 2020 by historians Professor Simon Szreter from the University of Cambridge, and Professor Kevin Siena from Canada’s Trent University, suggests that syphilis infections have been a far greater risk in the capital than around the provinces for at least 250 years.
In the late 18th century, at least one in five Londoners had contracted syphilis, known as “the pox”, by their 35th birthday, their research shows. They also found that Georgian Londoners were over twice as likely to be treated for the disease than people living in the much smaller city of Chester, and 25 times more likely than residents of rural Cheshire and north-east Wales.
Syphilis was first documented in Europe 500 years ago during the French invasion of Naples in 1495. Because it was believed to have been spread by invading troops, it was known in some parts of Europe - including the UK - as the “French disease”.
Mindful of the stigma, the French, however, called it “the Neapolitan disease”. It is thought up to five million people died across Europe during that outbreak, which left victims with bursting boils and rotting flesh.
But, while one theory is that the disease was brought to Europe by Christopher Columbus’s crew on their return from the New World, scientists have found signs that a subspecies of treponema pallidum - the bacterium that causes syphilis - was present in Europe as far back as the 12th century.
Today, syphilis is perfectly treatable. Symptoms include ulcers and white or grey warty growths on the genitals or bottom, sores in other areas, including the lips, mouth, and hands, a rash, flu-like symptoms, swollen glands, and possibly patchy hair loss on the head, beard, and eyebrows.
In extreme cases, it can cause serious and potentially life-threatening complications, if left untreated. But these are rare.
The latest government figures show 30 deaths were caused by syphilis in England between 2013 and 2021. The UKHSA says condoms are the best form of defence against sexually transmitted infections such as syphilis.
It urges anyone having condomless sex with new or casual partners to undergo testing, which is free, and can be accessed at sexual health clinics.
To find your nearest sexual health clinic visit: www.nhs.uk/service-search/find-a-sexual-health-clinic
