Jadon Sancho starts for Manchester United against Southampton.
The England international is one of two changes to United’s midweek win.
Back on track after making light work of Real Betis, the Dutchman is eager to put last week’s loss at Liverpool behind him.
Mired in a relegation battle, Saints have won two of their last three games in the Premier League including beating Chelsea away from home, making them no pushover for the third-placed Red Devils.
Therefore, Ten Hag is picks another strong side on Sunday afternoon - particularly with victory in their Europa League tie against Betis all but sealed.
Marcel Sabitzer is out after sitting out the first-leg win over Betis due to an unspecified injury.
Anthony Martial also misses out with the striker yet to return to full training following a hip issue. Christian Eriksen and Donny van de Beek are also sidelined.
Starting Manchester United XI: De Gea, Martinez, Fernandes, Rashford, Casemiro, Varane, Antony, Shaw, Sancho, Weghorst, Wan-Bissaka.