Raphael Varane is only fit enough for the bench, so Jonny Evans partners Harry Maguire at centre-half for Manchester United at Old Trafford.
Casemiro has lost his battle to be fit to face Manchester City and is not in the squad.
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United have made three changes from the side who scraped past FC Copenhagen in the Champions League in midweek.
The other changes see Antony and Sergio Reguilon drop to the bench for Christian Eriksen and Victor Lindelof, who is set to play at right-back.
Alejandro Garnacho is also on the bench despite his social media incident with starting goalkeeper Andre Onana this week.
Amad Diallo, Tyrell Malacia and Jadon Sancho are still unavailable but Aaron Wan-Bissaka is back in training.
Confirmed Manchester United XI: Onana; Lindelof, Evans, Maguire, Dalot; Amrabat, McTominay, Eriksen; Fernandes, Hojlund, Rashford
Subs: Bayindir, Mount, Martial, Reguilon, Garnacho, Varane, Antony, Mainoo, Hannibal
Time and date: 3.30pm GMT, Sunday October 29, 2023
Venue: Old Trafford
