Manchester United could be without Marcus Rashford and Anthony Martial for this weekend's derby at City.
Rashford and Martial did not participate in training sessions earlier this week and Martial has played only 45 minutes in two months due to hamstring and Achilles injuries. The Frenchman has not participated in a full training session since August 25.
Rashford suffered a muscular injury in the 3-1 win over Arsenal on September 4 and has not trained in three weeks.
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The pair missed United's Europa League games against Real Sociedad and FC Sheriff and Martial has not started for United since November.
United manager Erik ten Hag is expected to provide updates on Rashford and Martial at his pre-match press conference on Friday afternoon.
Ten Hag would have an additional training session on Saturday to allow any players struggling with issues to prove their fitness. England captain Harry Kane claimed Harry Maguire "played another five, 10 minutes, on almost one leg" of their 3-3 draw with Germany on Monday night.
Maguire is highly unlikely to start if he is fit as he has been on the bench for five of United's last six games and has not started in the league since the 4-0 thrashing at Brentford on August 13.
Raphael Varane was an unused substitute in France's Nations League defeat to Denmark on Sunday and has trained with United this week, while defensive partner Lisandro Martinez only played 12 minutes in Argentina's friendly win over Jamaica in New Jersey in midweek.
Donny van de Beek has also not trained with United this week and has been absent from the last three matchday squads with an unspecified injury. Aaron Wan-Bissaka has missed the last four games and Martin Dubravka did not travel to Moldova for the win against Sheriff.
If Rashford is unavailable then Ten Hag could start the same side that beat Sheriff in United's last game more than two weeks ago.
Possible United squad vs City: De Gea, Heaton, Dalot, Varane, Martinez, Maguire, Lindelof, Malacia, Shaw, McTominay, Eriksen, Casemiro, Fred, Iqbal, Fernandes, Antony, Elanga, Sancho, Garnacho, Ronaldo
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