As part of the deal, Sevilla have an option to buy the 20-year-old for £20million plus a further £3m in add-ons, the PA news agency understands.
United have also included a buy-back option and a sell-on fee if he departs elsewhere.
Hannibal joined United from Monaco in 2019 and has made 10 appearances this season but is expected to find his first team opportunities limited by the imminent returns of Casemiro and Mason Mount.
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