Erik ten Hag says he relocated Bruno Fernandes to a deeper role to offset the absences of Casemiro and Christian Eriksen. Eriksen was sidelined for 10 weeks with an ankle injury while Casemiro served the final match of his four-game domestic ban in United's 2-0 triumph over Everton on Saturday.
Fernandes moved to central midfield alongside Casemiro when he was sent off against Southampton last month but he occupied his usual No.10 role in the FA Cup quarter-final win against Fulham and the Premier League loss at Newcastle.
Ten Hag has started midfielders Marcel Sabitzer and Scott McTominay in all four fixtures Casemiro has been unavailable for but swapped Sabitzer with Fernandes in the midweek victory against Brentford and they remained in the same positions for the dominant defeat of Everton.