A 28-year-old man is fighting for life after being stabbed in Canning Town.
Police investigating the attempted murder said they were called by paramedics at 5.16am on Wednesday to reports of an injured man on Martindale Avenue.
He was rushed to an east London hospital with serious stab wounds, and remains in a critical condition.
Officers said the attack is believed to have occurred at the junction of Mandela Road and Coolfin Road.
The victim met with another man shortly before he was attacked.
Detective Sergeant Keith Faris, the investigating officer, said: “We know the victim met with another male shortly before he was attacked and we are appealing to anyone who was in the area at the time to contact police.
“Anyone who witnessed anything, no matter how small, is asked to call police so we can identify the person responsible for this man's serious injuries."
There have been no arrests and enquiries continue.