At least 18 people were killed and 13 injured in shootings in Maine, Governor Janet Mills has told a press conference.
State police told media that ten victims were yet to be identified as they warned the public not to approach the "armed and dangerous" suspect, thought to be behind Wednesday night's shootings at a bar and bowling alley in the city of Lewiston.
Eight of the eighteen victims were shot dead in the bowling alley, while seven were killed at a bar. Three victims later died in hospital, officers said.
Police officials believe the shooter was a man named Robert Card, a firearms instructor with a history of mental health issues. However investigators were still processing the crime scenes and working to gather evidence.
The gunman is still at large and hundreds of police officers are spread out across the north east US state searching for him. Residents in three towns have been ordered by police to stay indoors.