London Irish survived a stint with just 12 men to condemn Gallagher Premiership leaders Saracens to their first league defeat of the campaign.
The absorbing contest, which Irish won 29-20, was marred by two red cards and particularly concerning scenes as Saracens hooker Tom Woolstencroft received lengthy treatment after appearing to be knocked out.
Newly-appointed England coach Steve Borthwick was watching on as Saracens suffered their first defeat in 10 league matches as a poor start and ill-discipline cost them dear at the Gtech Community Stadium.