Substitutes Cody Gakpo and Darwin Nunez came off the bench to help turn around Liverpool's Carabao Cup semi-final first leg at home to Fulham and ensured they will take a 2-1 lead to Craven Cottage.
The pair were introduced early in the second half with the hosts trailing to Willian's 19th-minute goal after a Virgil van Dijk error.
Liverpool were struggling for creativity without the injured Trent Alexander-Arnold - who helped turn a 3-2 Fulham lead into a 4-3 Reds win in last month's Premier League meeting - but as at Arsenal in the FA Cup at the weekend Jurgen Klopp's changes altered the game.
Nunez added a directness which had been lacking while Gakpo brought the composure and control to midfield Ryan Gravenberch had not before he was replaced by his Netherlands team-mate.
And the pair combined for Gakpo to score in the 71st minute, just three minutes after Curtis Jones' deflected equaliser.
The last team to win at Anfield was Real Madrid in February. Before that it was another side in white, Leeds in October 2022, and Fulham - in their first League Cup semi-final - must have been encouraged by the start they had.
Klopp made six changes from the weekend and while that saw 20-year-old Conor Bradley deputise for Alexander-Arnold in only his second start of the season, it also included the return of Van Dijk.
The Netherlands captain was back after illness but his decision to head a ball aimlessly sideways on the edge of his area proved costly.
Andreas Pereira nipped in behind and cut the ball back to the penalty spot where a couple of neat touches from Willian opened up the space for him to fire through the legs of the recovering Dutchman and give goalkeeper Caoimhin Kelleher little chance.
Moments later Van Dijk was booked for catching Pereira in the face with an arm as his travails continued.
But his personal difficulties were matched by his team, who were too one-paced in their build-up.
Harvey Elliott was given Mohamed Salah's position on the right wing but his role often seemed to require filling the space usually occupied by Alexander-Arnold, which meant dropping deep with Bradley pushing forward as an orthodox over-lapping full-back.
But apart from an early Jones attempt straight at Bernd Leno and a Diogo Jota narrow-angle shot across the face of goal chances were rare with Fulham having more on target in the first half.
The tempo increased after the break with Gravenberch shooting wide and Jota delaying a fraction too long having created space for himself with a square run across the penalty area allowing Antonee Robinson to block.
But as the hosts pressed for the equaliser Fulham were able to expose the space opening up in Liverpool's defence and Kelleher got down low to parry a Bobby Decordova-Reid shot.
Alexis Mac Allister's cross was turned over by Leno but the equaliser had an element of good fortune when Jones took aim from distance and went in off Tosin Adarabioyo's back.
Leno was beaten again when Gakpo turned home Nunez's near-post cross after linking with Jota.
Liverpool's all-action Uruguay international could have all-but sealed Liverpool's passage to Wembley before the return leg but a full-stretch Leno tipped over his header, pushed away a fierce drive and blocked his close-range effort.
