King Charles has said his "thoughts and special prayers" are with the victims of the Turkey earthquake.
It comes after two major earthquakes struck southern Turkey and northwestern Syria on Monday, followed by a third quake with a magnitude of 5.7 on Tuesday morning.
The devastating death toll currently stands at over 7,000.
This evening in. statement, the King said: "My wife and I have been most shocked and profoundly saddened by the news of the devastating earthquakes in South East Türkiye.
"I can only begin to imagine the scale of suffering and loss as a result of these dreadful tragedies and I particularly wanted to convey our deepest and most heartfelt sympathy to the families of all those who have lost their loved ones.
"Our thoughts and special prayers are with everyone who has been affected by this appalling natural disaster, whether through injury or the destruction of their property, and also with the emergency services and those assisting in the rescue efforts."
WHO has warned the death toll from the earthquakes could hit 20,000 and warned 23 million people - including 1.4m children - could be affected.
UNICEF has warned that thousands of children may have been killed in Turkey and Syria.
Making a statement in the Commons, Foreign Secretary James Cleverly confirmed that three British nationals are missing and a further 35 are affected. He did not specify whether they were in Syria or Turkey.
He said: "We know that three British nationals are missing and the Foreign Office's Crisis Response Hub is working to support the at least 35 British nationals who have been directly affected by these earthquakes.
"We assess that the likelihood of large-scale British casualties remains low."
He said many of the 3.5million Syrian refugees hosted by Turkey reside in the affected provinces and that the country is requesting international assistance "on a scale that matches the enormity of the situation that they are facing".
Meanwhile, footage has emerged from Syria showing a baby girl taking her first breath surrounded by destruction, after her mother went into labour during the quake.
A miracle baby who was born under the rubble of collapsed buildings in Afrin, in the northeast of the country, has devastatingly been made an orphan as her parents did not make it out alive.
Little is known about the newborn baby and its now-deceased family, aside from reports they had already been displaced by Syria’s brutal war from Deir Ezzor to Afrin, some seven hours away.