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LiveScience
LiveScience
Kenna Hughes-Castleberry

Keratin may act as a 'brake' for skin inflammation, pointing to potential treatments

A close up of a person's right forearm, covered in red circular rashes. Their left hand scratches the forearm.

Keratin proteins form our skin, hair and nails — but when mutated, they can mess with the immune system, driving diseases like psoriasis and eczema, new research suggests.

In the new study, published Wednesday (April 8) in the journal Science Translational Medicine, researchers identified a mutant keratin protein that can disrupt processes that normally help skin cells manage inflammation. That breakdown could help to explain how inflammatory skin diseases emerge.

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