Mohamed Salah and Sadio Mane drop to the Liverpool bench as they aim to secure a place in the Champions League semi-final against Benfica at Anfield.
Jurgen Klopp has rested his two forwards ahead of Saturday's FA Cup semi-final with Manchester City as Roberto Firmino, Diogo Jota and Luis Diaz make up the front three against the Portuguese.
Virgil van Dijk, Andy Robertson and Trent Alexander-Arnold are also part of an extremely strong Reds' bench as Joe Gomez, Ibrahima Konate, Joel Matip and Kostas Tsimikas complete the back four.
Gomez filled in for Alexander-Arnold at right-back against Watford earlier this month and is once more at full-back at Anfield.
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In midfield, Jordan Henderson and James Milner will patrol as Naby Keita once again starts against Nelson Verissimo's side having caught the eye in Lisbon in the 3-1 win last week.
Fabinho, Alex Oxlade-Chamberlain and Curtis Jones are just three of the midfield options on the bench for Klopp as Harvey Elliott is also named as part of the substitutes.
Victory this evening will set up a semi-final clash with Villarreal after the La Liga side went through 2-1 on aggregate against Bayern Munich.
Liverpool: Alisson; Gomez, Matip, Konate, Tsimikas; Henderson, Milner, Keita; Jota, Firmino, Diaz.
Subs: Kelleher, Fabinho, Van Dijk, Thiago, Mane, Salah, Oxlade-Chamberlain, Jones, Robertson, Origi, Alexander-Arnold, Elliott.