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Joe Manniello

Joe Manniello's Week 17 NFL picks

Week 17 is brought to you by your favorite headache medicine. Why? Well, in addition to being the second-most difficult week of the season to predict (we’ll see you in September, Week 1), there are so many different scenarios for the playoffs that your brain will need to call a timeout. Motivation and desperation are everything this week.

Favorites went 7-8-1 ATS last week and are 106-121-8 for the season. Home teams went 9-7 straight up and 8-7-1 ATS, bringing their totals to 118-121-1 and 112-120-8.

My three most confident picks are Buffalo, the L.A. Chargers and Indianapolis. Avoid Minnesota-Detroit and Las Vegas-Denver.

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