In 2007, the then-Oakland Raiders selected LSU quarterback JaMarcus Russell with the first overall pick in the draft.
That did not go well.
Over three NFL seasons, Russell completed 52.1% of his passes (354 of 680) for 4,083 yards, 18 touchdowns, 23 interceptions, and a passer rating of 65.2. His 2008 season was actually decent, as he completed 198 of 368 passes for 2,423 yards, 13 touchdowns, eight interceptions, and a passer rating of 77.1. But in 2009. Russell was benched by head coach Tom Cable (who had replaced Lane Kiffin the year before), and the team released him in May, 2010. Aside from a few efforts to stay in the league, we never heard from Russell in an NFL context again.