Adil Ray aimed a dig at the government as a minister failed to show for an appearance on Good Morning Britain on Wednesday.
The Prime Minister is still hitting the headlines amid the latest claims he had a birthday celebration inside No 10 during the first lockdown.
It comes amid a string of party allegations while the country was under some of the strictest coronavirus restrictions.
The latest allegations emerged on Monday when Downing Street was forced to admit that Downing Street staff "gathered briefly" in the Cabinet Room following a meeting after it was alleged 30 people attended and shared cake despite social mixing indoors being banned.
READ MORE: ITV Good Morning Britain fans complain over 'rude' Ed Balls remark to Richard Arnold
ITV News reported the Prime Minister’s wife, Carrie Johnson, had organised the surprise get-together complete with a chorus of “happy birthday” on the afternoon of June 19, 2020.
The number of allegations now total at least 19 separate events.
Shortly after GMB began this morning Adil, who is presenting the ITV show alongside Susanna Reid, told viewers that the programme didn’t have a minister ready to appear to answer questions.
"We’re hearing this morning, as often happens when there’s a big news story around for the government, when they’ve got their backs to the wall and they need to answer questions – is that they disappear," Adil began.
"So we are hearing that we may well not get a government minister this morning despite being a national breakfast show that has a predominantly Midlands and North-based audience as well, so the fact that the ministers are ignoring a big section of the UK this morning I think is very telling."
He later added: "You have one job in the middle of a pandemic as a leader. You don’t know much about the science – follow the science, explain the rules, and follow the rules."
"His own personal advisor broke the rules, he has to get rid of him. His health secretary broke the rules, he had to get rid of him. And now he himself at the centre of a criminal police investigation.
"You couldn’t make this up! It’s the worst possible situation."
The absence of a government minister still hadn't changed over an hour into the programme when Adil made his remarks.
After speaking about the rising number of Covid-related school absences, Susanna said: "We would like to take to a government minister about it this morning but unfortunately, we can't.
"But we'll keep you updated on that situation."
After showing an empty chair reserved for a minister in Westminster, Adil then commented: "If any government ministers are around we do have some cake over here if you'd like to come in or we can ambush you," as co-star Charlotte Hawkins held up a chocolate cake with 'Happy Birthday' written across it.
"Some cheese and wine are around as well so lots of reasons for you to pop in if you'd like to," he added.
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