
Since it first captured headlines in the 1980s, the human immunodeficiency virus, better known as HIV, has been a tough nut to crack. It’s not for a lack of trying, however. Science has come a long way in parsing out the virus’ operating manual and developing drugs, called antiretrovirals, that suppress or prevent it from replicating. But because of some nasty tricks up its sleeve, fully eradicating HIV has been damn near impossible.