Melbourne have steamed past an injury-ravaged Brisbane by 56 points to claim a perfect 3-0 start to the AFLW season.
Elsewhere, Port Adelaide (2-1) lost star forward Indy Tahau to a suspected serious knee injury, overshadowing a thrilling four-point win over GWS in Canberra.
Tahau, who previously tore her left ACL, was helped off with a right knee injury late in the third quarter of Port Adelaide's 7.10 (52) to 8.0 (48) victory at Manuka Oval.