The “bible” of clinical psychiatry – the DSM, short for the Diagnostic and Statistical Manual of Mental Disorders – is one of the most popular psychiatry reference books around the world. Clinicians use it to diagnose patients and scientists use it to guide research.
Despite its wide impact, the DSM has never integrated biology in its diagnoses of mental illness. This omission was largely because the underlying biology of mental illness was too preliminary to be included in such a widely used clinical manual.