Ian Blackford has accused Liz Truss of "ignoring the damage and the chaos" of her mini-budget that plunged the markets into turmoil due to her unfunded tax cuts.
The SNP's Westminster leader also took aim at the Prime Minister saying she was more concerned about saving the Chancellor Kwasi Kwarteng 's job than making sure the poorest in society will be able to heat their homes this winter.
He said: "The reality is that the Prime Minister is ignoring the damage and the chaos of the mini-budget. She is worrying about saving the Chancellor's job, but many families are now worried not just about heating their homes, but keeping their homes, Prime Minister.
"The only thing growing under this Government are mortgages, rents and bills. Is that what she really meant when she declared herself a pro-growth Prime Minister?"
Truss replied that the Government had "taken action on helping families heat their homes" and noted that interest rates were rising globally.
The Prime Minister added: "I want to do all I can to help families across Britain and the way we are going to help them is by delivering economic growth by making sure we have the jobs and opportunities in Scotland and right across the UK."
Blackford also accused Truss of "scapegoating" the Governor of the Bank of England in order to save Kwarteng from the impact of the mini-budget.
The MP for Ross, Skye and Lochaber said: "When the Prime Minister last stood at the despatch box, the average two-year fixed rate mortgage stood at 4.5%, they are now at 6.5% and rising, hitting average families with an extra £450 a month on mortgage payments every single month over and above what they were paying.
"37 days into the job, this is literally the cost of the Prime Minister 's incompetence. It is the price households are paying and all because of a Chancellor that she chose. Will she now give up her desperate plan to save her Chancellor's skin by scapegoating the Governor of the Bank of England?"
The Prime Minister replied: "The action we have taken has meant that families in Scotland and across the United Kingdom are not facing gargantuan energy bills."
Truss called on the SNP to encourage the building of more nuclear power stations and more North Sea gas extraction, to "help deliver on a more secure energy future for all of our people".
Responding to the Prime Minister, SNP Westminster leader Ian Blackford said: "If she wants to ask us questions, we can swap places.
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