I tried polynucleotide injections to rejuvenate my hands - here's what happened, with photos

Square image of woman's hands on bed linen with a pink fine line drawing overlaying the top left corner, set in front of pink polka dots (bottom right) against a pastel blue and pink ombrebackground .

I don’t think it’s a stretch to say that polynucleotides are one of the most talked-about – if not the most talked-about – aesthetic treatments of the last couple of years.

This rejuvenating injectable treatment is much raved about for its promising results in skin rejuvenation, particularly for the under-eyes and other areas of the face. But it can be administered to the body too, and polynucleotides for hands are gaining ground as one of the biggest 2026 aesthetic trends.