Childhood cancer survivor Joanna Gold (Vanessa Bayer) is still living a forcibly sheltered life with her parents in Cleveland when she auditions for and gets her dream job as a presenter/hawker on shopping channel SVN. A new life in Pennsylvania beckons, among the stars she grew obsessed with during the treatment that isolated her as a child. Alas, on her first day her product is switched at the last moment to a rancid pillow mist whose smell catches her off guard. Her expression is enough to get her fired by magisterially ruthless (“Don’t just walk up to her as if you’re a human being on the same level!”) CEO Patricia (Jenifer Lewis). What is a girl to do but play the sympathy card and pretend her childhood cancer has come back?