Around 100 firefighters have battled a huge blaze which destroyed part of a building containing a department store in Peckham.
Fifteen fire engines were called to the blaze on Rye Lane on Thursday evening.
Videos circulating on social media show thick black smoke billowing into the sky as crews work to tackle the blaze.
Other footage shows people gathered in nearby Copeland Park, a popular events venue in the area, filming the blaze with their phones.
Fire in Peckham earlier this evening.. pic.twitter.com/SuoM8nG477
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London Fire Brigade initially said the fire was at a shop and a storage unit.
Local residents were advised to keep their windows and doors closed.
No was was injured in the blaze. The cause of the fire is under investigation.
Station Commander Craig Abbott, who is attending the scene, said: “Firefighters worked hard in arduous conditions to bring this fire under control.
“A single storey extension to a department store on the first floor of a commercial building was destroyed by the fire.
“Around 50 people left the building before the Brigade arrived. There are currently no reports of any injuries.
peckham fire over copeland, seems to be getting worse by the second pic.twitter.com/Pn0GHd3chQ
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“A significant amount of smoke was produced by the fire and local residents were advised to keep their windows and doors closed.
“Traffic in the area was also impacted and members of the public were advised to avoid the area.”
Two of the Brigade's 32-metre turntable ladders were used as water towers to help fight the fire from above.
Control Officers took the first of over 40 calls at 8.54pm