
The biggest rivalry in Mexican soccer highlights the 2025 Concacaf Champions Cup round of 16 matchups.
Club América and Chivas will face off in a continental Clásico Nacional for the second year in a row in the Concacaf Champions Cup round of 16. América dispatched Chivas from the tournament in 2024, on the back of a dominating first leg 3–0 win at Chivas' home.