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Sports Illustrated
Sports Illustrated
Sport
Tyler Lauletta.

How 49ers' RB Depth Chart Shakes Out If Isaac Guerendo Misses 'TNF' vs. Rams

Isaac Guerendo catches a pass for a first down against the Chicago Bears. | Cary Edmondson-Imagn Images

The San Francisco 49ers have once again been bitten by the injury bug.

This year, it’s the running backs room that has been most affected. Superstar running back Christian McCaffrey missed the first half of the season do to a lingering injury, and was only able to play in four games before landing on the IR again. Jordan Mason, who had performed admirably in McCaffrey’s absence, joined his teammate on the IR the very same day.

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