Advocates for legalised voluntary assisted dying say their fight to allow euthanasia in NSW isn't likely to be realised this week.
NSW is the only state in Australia that does not allow assisted dying for terminally ill people.
Supporters of the legislation are rallying outside NSW parliament but say political opponents to the bill seeking to make the practice legal are likely to seek amendments on Wednesday.
"We have waited a long time, as in 50 years Dying With Dignity has been campaigning for these laws," Shayne Higson, president of the NSW branch told AAP.
The bill will return to the upper house on Wednesday evening after it was debated last month with 13 speeches given, including nine in favour and four against.
The bill passed in the lower house last year with a margin of 20 votes, after being introduced by Independent MP Alex Greenwich.
"We have to keep the pressure up, because we know that the legislation is not supported by our premier (Dominic Perrottet)," Ms Higson said.
"Fortunately, there are enough MPs in NSW parliament who reflect the support in their communities and now that support is also being shown in the upper house."
Steve Offner from Go Gentle Australia said the bill was unlikely to pass the upper house on Wednesday, was hopeful it had the numbers to pass next week.
"We're quietly confident that this evening there'll be a second reading vote which will be the first vote in the upper house," he said.
"Nothing is likely to happen today in terms of a final resolution, but we're hopeful that maybe next week, we'll see a final (resolution)."
