It's been 15 years since the Writers Guild of America (WGA) last went on strike.
That strike went on for 100 days and cost the California economy more than $3 billion.
The latest strike has come at a vastly different time in the entertainment ecosystem, with streaming services gaining prominence in the intervening years.
So, which shows will be affected by the current strike?
Here are some of the shows you might be watching now that will be impacted.
Late-night shows
Late-night talk shows such as Saturday Night Live (SNL), Jimmy Kimmel Live!, The Tonight Show with Jimmy Fallon, The Late Show with Stephen Colbert, Late Night with Seth Meyers, Real Time with Bill Maher, Last Week Tonight with John Oliver and The Daily Show have been immediately impacted by the strike. They have gone dark and most will air re-runs.
Former SNL cast member Pete Davidson was due to host the show this week but the episode is now in jeopardy.
On Monday's Late Show, host Stephen Colbert said the nation owed a lot to unions.
"Everyone including myself hope both sides reach a deal," Colbert said.
"But I also think that the writers' demands are not unreasonable".
Daytime soap operas
Shows such as Days of Our Lives, The Bold and the Beautiful and The Young and The Restless have some episodes in the can, but often shows are written and filmed over a short period of time.
It is therefore likely that if the strike continues for some time, daytime soap operas will be impacted.
Abbott Elementary
Although Emmy award-winning show Abbott Elementary appears on a streaming service in Australia, it is a network television show in the United States, meaning it will be impacted.
Writer Brittani Nicols has told independent global news agency Democracy Now! that writers are the backbone of the industry and studios are in for "a rude surprise" as a result of the strike.
"We are a show that writes while we air," Nichols said.
"And so, if this strike goes on for a significant period of time, our show will not come out on time and that could change the amount of episodes, which people I'm sure will be very upset about.
"It could change the air date. It could change a lot of different things because there just will not be things going into that pipeline."
Yellowjackets
The current season of Yellowjackets has finished filming. But show co-creator Ashley Lyle has confirmed that writing for season three of the series has come to a stop after just one day in the writers' room.
"I'm really excited to get back to it as soon as the WGA gets a fair deal," Lyle tweeted.
Cobra Kai
Co-creator of Cobra Kai Jon Hurwitz has tweeted that the writers' strike may impact season six of the show.
"We hate to strike, but if we must, we strike hard," Hurwitz tweeted.
"Pencils down in the Cobra Kai writers room".
Why some of your favourite shows will still be available
The final seasons of popular shows such as Succession and Barry are currently streaming and will not be impacted because production on them wrapped up some time ago.
Highly anticipated shows such as Queen Charlotte: A Bridgerton Story have also wrapped production and will stream as normal.
The Los Angeles Times and Variety are reporting that scripting has also been completed for all episodes of season two of the Game of Thrones prequel House of the Dragon.
It's shows that are currently shooting that may be impacted such as season three of Hacks.