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USAFacts
USAFacts

Heart disease causes one in five American deaths

Disease Heart Disease CDC United States diabetes Cholesterol

In 2021, the heart disease mortality rate in the US was 209.6 deaths per 100,000 people, meaning heart disease caused about one in every five deaths. Heart disease has been the leading cause of death in the US since 1950.

“Heart disease” is a broad label for various heart conditions, including coronary artery disease (CAD), the most common type. CAD killed 375,476 Americans in 2021.

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