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WhatToWatch
Entertainment
Terrell Smith

Grey’s Anatomy season 21: next episode info, trailer, cast and everything we know about the long-running medical drama

Chandra Wilson Ellen Pompeo Harry Shum Jr Meredith Grey Hulu
Kevin McKidd as Owen surprised in Grey's Anatomy season 21.

TV’s longest-running medical drama in primetime returns for more tear-jerking moments and intriguing storylines with Grey's Anatomy season 21.

The series continued to captivate fans in season 20, and while season 21 will of course include many things that are familiar, there will be some noticeable changes. We're talking cast departures and even a brand-new showtime. Curious as to what we mean?

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