George Shapiro has died of natural causes at the age of 91.
The Seinfeld producer and manager to a host of stars including Andy Kaufman, Jerry Seinfeld and Carl Reiner died at home in Beverly Hills on Thursday, according to Deadline.
No further details have yet been released.
As well as running his own talent company and managing a number of big names, Shapiro was well known for being producer on several hit TV shows.
Among those he was involved with - as well as Seinfeld - included The Steve Allen Show, That Girl and Gomer Pyle.
As well as being producer on comedy series Seinfeld, Shapiro managed the star comic and produced a number of his standup specials.
These included the likes of the Netflix show Jerry Before Seinfeld and 23 Hours to Kill.
His last production was The Super Bob Einstein Movie which was released on HBO last year.
Following the news of his death, stars and fans alike took to social media to share messages of condolence.
Among those tweeting was veteran producer Norman Lear, who wrote on Twitter: "One of the dearest people I have ever known, George Shapiro, just passed.
"I bless our friendship and, at 99, I’m sure I’ll see him relatively soon."
He also shared a picture of the pair together.
Another user also tweeted: "It can't be overstated what a mark this guy made in cultivating comedy.
"You saw the 'Shapiro/West' vanity card on something and you knew you were getting the real "goods"... Man, we're losing them at a rate of knots lately huh?"
A third penned: "I’m heartbroken. George was simply one of the most caring humans and he will surely be missed."
And a fourth wrote: "RIP to George Shapiro, who started in the mail room at William Morris and went on to Manage Carl Reiner, Jerry Seinfeld and Andy Kaufmann. He was also an Executive Producer of Seinfeld."
Shapiro is survived by lifelong friend and mother to his kids, Melody, his son Danny, daughters Carrie and Stefanie and his five grandchildren.
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