
The FTSE 100 closed lower on Wednesday, held back by falls for drugs firms GSK and AstraZeneca, while oil surged amid reports that the US is eyeing a longer blockade of the Strait of Hormuz.
The FTSE 100 closed down 119.68 points, 1.2%, at 10,213.11. The FTSE 250 ended down 198.55 points, 0.9%, at 22,200.87, but the AIM All-Share rose 1.53 points, 0.2%, at 788.43.