French Prime Minister Jean Castex on Monday handed his resignation to President Emmanuel Macron, the prime minister's office said.
Castex's move cleared the way for a long-awaited cabinet overhaul by Macron who after his re-election in April has said his new government team should be more "concentrated", with less ministers.
Macron, who needs to send a signal he has heard the frustrations of voters expressed in low turnout and big support for the radical far-right and far-left, has said he was looking for someone with green and social policy credentials as prime minister.
His allies have said he will most likely appoint a woman, who would be the first since Edith Cresson briefly occupied the top job during the presidency of Socialist leader Francois Mitterrand in the early 1990s.
Such a profile could help counter the challenge mounted by hard-left veteran Jean-Luc Melenchon who reached a strong third place in the presidential election, allowing him to rally a broad coalition of France's left-leaning parties in the June 12-19 parliamentary vote.
(Reporting by Elizabeth Pineau, Writing by Tassilo Hummel, Editing by Dominique Vidalon and Ed Osmond)